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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef00fc10cb7e99f9950cdb45bf6413eaa7f6d2b6c47fcf1527203d2820fd9920' 
  AND token = 'NHk6fqXbCkMcGgLQmXyS3fzFG5TeuaajxW6J7Md+ts0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}