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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25971fdedf12037100aef091d08c30eea3853896f6a8b66795917587b68f6b11' 
  AND token = '2JZydDbYbk3vWHq0g4a0tKHUeOOV/2JiIXP0d/4PR/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}