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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2387a5f9b11b8020916b31c1a0e8fa9db093e00f5c3e8978df1ed18141f7d2d5' 
  AND token = '3n2/z/rX7nfQ8+B/8RHMeMg6NfwSixd9fnJt77yYi3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}