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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c065178ccbc7c76ac8f14cc0517c358933b03f34da70d1f64569885d1aac1b95' 
  AND token = 'TIi/8h7uOIAlyHKhQ0wY5X36E0JlnrJ8iZ8DnkyG52c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}