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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45bf474bcccd30c8e45af6e813eb775b58c135551504cd402f238d8fa52c00f9' 
  AND token = 'zv8oZef1wLbyCpcYQSCGaT4Xyo5gyNt8V+nlUZvr8qI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}