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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ba74ffd03b25f721d8d50b1f746d79d12bee1066d9eceaf46338dffbd977a53' 
  AND token = 'YmCX8ZikKx0gUwABSxKTSFReM733Z4C0Bby2LOn8xoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}