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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4d240a8f8e8142d54af2aa2c2e153d2c7d2a8267f09d301854f12e6b74466ea' 
  AND token = 'EXV5Bmx4qQBVkoBykn/ZuYD79e/PMsl+6d8Z0h2kCwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}