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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f58a4ba3fadf2c91f72a52195ba6d4532ed8e3caa3c08f47c5b7a0195557c04' 
  AND token = 'psxaSdLapbNrgDsoU4r9H1P2IXUZXNyc8xiS9vmtpuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}