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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34668f414778573a96737e510e0978ac3cba864efaa327bb2b805b5426ead604' 
  AND token = 'M0T9NXDL5Qxa3lNXsXn+RqwYek5ydxtfO3BY79PHm/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}