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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63380680604fe4ad96a150ad32d9745dc5c3d59a95cef6850517c2c3ce7005f6' 
  AND token = 'vw/gpFrhsQ26BYZc66ZrA5MfY21E2ZxE0Dbi2O0Hs64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}