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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7ebde6a6cbc96d3ae167007701cb0591f54665226b88e52a62d018dc73d4f76' 
  AND token = '4eZ4ldcvgV/500g9hfe2S/2xoGFrTsLG3G/UJHzW/1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}