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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d6669c732ded148ec4f43b8798d696e967c52d679a8704b2df291af613d834' 
  AND token = 'ZUc1rIwHPWR6ChzqpAluxS22jTErR7z1t2H+vIg2w+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}