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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23bf37722f7fc017095960a9fab313f1b44ff5d67e79652fda64eb55d6a33310' 
  AND token = 'yZKW0uT+VD2CVz5hlov41ViVywfAl4zn2QwMy44RgLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}