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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14dd72bd092f19f31a2687c392e7343bdb1d188eef863991919d2de39e8895cc' 
  AND token = 'J6hPqi5oTEfCZ4wRfi+8tQu8TA9q4HymebBx5emqyYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}