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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '782df100fa1c579f357b33feb75377d4029166917c2047aeb9a25709961a51a0' 
  AND token = '3OdlqX/9SN7636HCfsiMScZqbumjTbaQXmRAGtg5rvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}