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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61563d94d4cb75b830d4267369b7ec2c874ca10abffc0caf723ee854677e391f' 
  AND token = 'o3YCgkHsJXQJSyhVDdtoyfrwp8DA6qCThdmYNoFmDS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}