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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58a3db626f1596924a9989f716298bbc77f0eb91a3345e4ce04e58127a175336' 
  AND token = '8v6GnYycDiGILxQ50MD6Gp8ONIih8Dymf9RL0+pO7kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}