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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d746fabf9947e4f4b9c96350fae4506c6d4ffee6949bd50c27f666df19111a9' 
  AND token = 'dMlcXDofDD56X+ASCof0QpQI9vBLnWFJTYPzoCePGrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}