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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46dcea191abdbc701a11edd0158401716a5b0e547132de2e7248e8debd143ea1' 
  AND token = '2w5n1hwJkAmlGGeeQ1cqX66+7BgunwWDRzku1MRGF7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}