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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bed5aaa9a720c17952103916c074fa8e7456a6903637636ba27e8ca0d8ce293' 
  AND token = 'w+35r9ARZ55yUfcsA+n321TWboDno+aJeq7Ze+cPG+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}