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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0c5dc48b1efde1a4de0094c0b1783d255f25748785574d1d32551ea7c04b2e1' 
  AND token = 'aC44iZ8cvyIGjA8J4wG9K8Ly3AYaTX6qL3Uqv3Aey6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}