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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38de2c668d4e764ac5b39f865774c412b93b20e40e2a3003e749aa8f19d6453' 
  AND token = 'VRbyoEHS63uQ/to39uBLQZ3zyT1X0QKqWlsnFyayyS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}