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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaf303eb6e133804db1b4aa18659a7db39d5c499c3fc427e68b15449b0bee2fe' 
  AND token = 'F8cwwc9dU206gF5K20yY6RV7E4omNtiPkUoskTNJyEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}