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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8efcbde4a134adc5ba61674e4eac5e7a0448db946d5f4c4f9ac14df7654a59b' 
  AND token = '3SF2D2Gm6Lcie3Wp9pYTNIJP10ER0D5x2PfZkZnIDTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}