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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c03295814a23fd39f1e4d146a535f16d7b927463a2ad2e07ba3ca644c991736f' 
  AND token = '+/eheaBCTJddXMyE1hOkADz3SAZLoiwjx66h1S8a7HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}