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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fea92c39c0619304e4f11d87bdeef580b8b9fff6969d3e82f3c033b57b998c59' 
  AND token = 'ymMB5k0O4BexHcV8hw1AAl0EB3sMmDKyCBNJCFwdYQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}