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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c88e59fd9a6b2470e2b18a8cfebd5116d970510de01af9675ca9cf0366bb86' 
  AND token = 'TOSEAqyVc/eeRGN0XzFelDzKHx4RikQV0vlJa6s6Fz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}