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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '505d3528a964c9587a94f2019803656710cc06d20436dfe48facc37592568d9a' 
  AND token = 'b7h+M3q6CY4/st/pD9FpP5Z0CfwzE6Xud7iBCi2qXaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}