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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af1f0fcd8edf4357fe489020d50f57d620a8e0ef9f92d23438038b6b16f2b18f' 
  AND token = 'vWOrnpjtJ+cVgaoCHjgF0Ye8UB9MQ0KStFfwW076ONM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}