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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b64fa04508a5617bb461c759bf8e3cdc4da58817513336fa0d36d8884881839c' 
  AND token = 'DCY4Jmj5lT40yndgjZnbmvbe88SAO4ZRsMGggzfmzu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}