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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4be5a95599f325003a6695591ba5e3b4f90a80ad9fcfdbc59c6abf5cd769981' 
  AND token = 'OlBJMc0E7Wx3WaA8Tqmg8/wg/QAMc7CLf7vgGiP55Zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}