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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a6f7ff6223e94b2c6b1255265b1d40db12eb2011df7f98f530488d5e65d5707' 
  AND token = 'qckbLHp/9W2ew9u0ZhpsGhTsSr42WnZkV33qZpuoxtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}