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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44430373b063420676b3d6a64406a2e3b0715d51aea385a23c9d42d060a1f293' 
  AND token = 'wk4dUykgDEYFirGi1enN5IDV9Q2//FEoWseKX3QeyNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}