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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5992d67c7a084ec9be98df4958a36b654cef3cc07ad026267e2e393c1fdec6' 
  AND token = 'icHS9d+ZF/kzJM1zkOK3Q4LErUS7tMm4ZyXBVliyh4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}