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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e907fdb6cd201a7296af804ed5aeb3c5baf8c1632ac468ed04978780ec3121d4' 
  AND token = 'DI9y3p1Gp934eLHqk97Hw8OYH8LsaxcfK+xc59WZWQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}