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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d755ac66fa138ba64e1321dea8218799e25b5e528eec37ee00e199c4ed4c887' 
  AND token = '8HBqVhu3gnCPaGD8T/loKKekEZwnmsIteUUL/Mqyegw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}