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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1222e8625eae7e5b2fd2f991600148827a3ca4bb51875cef64351f55505d94f3' 
  AND token = 'vB49H4L3j/1syZCxNdseLvL/1jelthG+0NfN1FmGFKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}