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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab254d76666e06b735b88128f30a74dfb78715d5d89bbd6d38fbd4a2299cf1f1' 
  AND token = 'SLGYh1hAS/1XTbbI6+nNxhBfx2f/joGXLJ6Obx5Q+zE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}