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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0d0cae60c024c76e0053d37b688980fab9b0455d23d60c296fea4e9e683f74c' 
  AND token = 's1uqjS8LGlAlA84VAuX4KK9RJm8o1wfwt6U77x1xY5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}