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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a414a6e672c536fb9802fcc23f3a08d7ef848a17de18f2092604c15a0d46019' 
  AND token = '7Qk1zzQT0cCUvV0rmNm6I839oqCf/GlDBGn6A17AglY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}