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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1efb96d2efe6b4db63c54f23754cc85490dca0d3aafdfe5288fb3c50d29d2cd6' 
  AND token = 'kOe6nXhTbVzW6t2XJp4qt6nNQObVjoLhmdI7XdjDzc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}