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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d2f8765f6b31f37bc66ba2332aeaea94021df86c817e3d0635219d9a1ea4a25' 
  AND token = '4hPGL/eXd81G/LF02dOonyCKvEuxSyK+cvu8xOa8q6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}