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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '112d597e4c1bc14f283f5a8ef51644af7b981e4daf07a2a432c178e952994a32' 
  AND token = 'fFyRILmkDsPDV2epzTx88N9RDbDx55quv6CL3aumf2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}