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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22a8158f8c8591545bc2cae746ad7d17573f2134d6e99fdb9642d475968eed9' 
  AND token = 'lnKXc4XApVOSAaU1LxLmFakXoKmM7Z4JkQjyEp5a7X4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}