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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3afc9f13b2de3853e8e9ff3b016038e783a90b28384e1ec4063b8070f3cb9365' 
  AND token = 'TQKr1Z4ed4+hDE5ht8YKRkSBZF7ltRbXEYBcKANtz9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}