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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a60212b965afd00213ed588d8aac273577fd09336598effdd7c3c5e66ba487ce' 
  AND token = '1LP/i9QNHEwLuHM1G0xE5y0IE8AwHEb0s6H4fMIN7+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}