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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6fa9df0f9cf3387cad217a7812b0bcc00636c4d58ef6e3b621be5ba3ec2c75' 
  AND token = 'w7Lba1PqEmKmT9r8chRNO+rO3mywGVDK7y6072IKDNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}