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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143993a614bc440306c0d2a65b824a35bbc5a379d102582f6af8b9e42f9ed80d' 
  AND token = '2t8cigktfzu/pMERW/EXXMqp96klij/Llb17kPs9/cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}