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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0750d267292cefc46a8387d56174092cb734b921927c2f8884f3ac8bd59bbce5' 
  AND token = 'TkzyfCtIqRQbx4jQw4LYGLml3Sfa3eG6fSYfXz9P+z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}