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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb01185ac8d3ebb3576854abc4c343982f9d91313baa4789429603da407d0202' 
  AND token = 'jUN42hokexe3w2mRDXdc/3axIjWfUK2VVvi3hABmS+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}